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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VDAC1
All Species:
43.64
Human Site:
Y225
Identified Species:
73.85
UniProt:
P21796
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21796
NP_003365.1
283
30773
Y225
R
F
G
I
A
A
K
Y
Q
I
D
P
D
A
C
Chimpanzee
Pan troglodytes
XP_001151901
283
30732
Y225
R
F
G
I
A
A
K
Y
Q
I
D
P
D
A
C
Rhesus Macaque
Macaca mulatta
XP_001107652
283
30703
Y225
R
F
G
I
A
A
K
Y
Q
I
D
P
D
A
C
Dog
Lupus familis
XP_536597
256
28121
N214
N
L
A
W
T
A
G
N
S
N
T
R
F
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q60932
296
32333
Y238
R
F
G
I
A
A
K
Y
Q
V
D
P
D
A
C
Rat
Rattus norvegicus
Q9Z2L0
283
30737
Y225
R
F
G
I
A
A
K
Y
Q
V
D
P
D
A
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510394
343
37536
Y238
R
F
G
I
A
A
K
Y
Q
L
D
P
D
A
S
Chicken
Gallus gallus
NP_001029041
283
30688
Y225
R
F
G
I
A
A
K
Y
Q
I
D
P
D
A
S
Frog
Xenopus laevis
P81004
282
30052
Y224
R
F
G
I
A
A
K
Y
Q
L
D
S
H
A
A
Zebra Danio
Brachydanio rerio
NP_001001404
283
30608
Y225
R
F
G
I
A
A
K
Y
Q
I
D
S
D
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94920
282
30532
Y224
K
F
A
I
G
A
K
Y
Q
L
D
D
D
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21752
283
29942
Y225
D
Y
A
L
A
T
K
Y
A
P
S
R
D
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P04840
283
30410
T223
N
V
N
I
E
F
A
T
R
Y
L
P
D
A
S
Red Bread Mold
Neurospora crassa
P07144
283
29981
Y225
G
L
E
V
A
T
K
Y
R
I
D
P
V
S
F
Conservation
Percent
Protein Identity:
100
98.9
99.2
86.2
N.A.
94.2
98.5
N.A.
72.3
95.4
75.6
85.5
N.A.
58.2
N.A.
40.6
N.A.
Protein Similarity:
100
98.9
99.6
87.2
N.A.
95.2
99.6
N.A.
77.2
98.2
91.8
93.6
N.A.
75.9
N.A.
60.4
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
86.6
93.3
73.3
86.6
N.A.
60
N.A.
26.6
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
93.3
93.3
80
86.6
N.A.
73.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.4
31.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47
51.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
0
79
79
8
0
8
0
0
0
0
79
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
36
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
79
8
79
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
72
0
0
0
8
0
0
0
0
0
0
8
0
8
% F
% Gly:
8
0
65
0
8
0
8
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
79
0
0
0
0
0
43
0
0
0
0
8
% I
% Lys:
8
0
0
0
0
0
86
0
0
0
0
0
0
0
0
% K
% Leu:
0
15
0
8
0
0
0
0
0
22
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
65
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% Q
% Arg:
65
0
0
0
0
0
0
0
15
0
0
15
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
8
15
0
8
29
% S
% Thr:
0
0
0
0
8
15
0
8
0
0
8
0
0
0
8
% T
% Val:
0
8
0
8
0
0
0
0
0
15
0
0
8
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
86
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _